Jonathan Oesterle

The paper introduces a large-scale dataset of functional responses from mouse ganglion cells, enabling population-level analyses and computational modeling of retinal computation.

Eyewire II provides a large-scale EM dataset of the mouse retina, enabling cell type annotation and connectivity mapping through human-in-the-loop deep learning and functional alignment.

This paper incorporates inhibition into deep neural networks for neural prediction, showing it improves surround suppression learning but not cross-orientation inhibition.

The paper examines how photoreceptor degeneration in rd10 mice affects the resilience of different functional retinal ganglion cell (RGC) types, finding differential vulnerability among response types.

This study investigates how nitric oxide modulates contrast suppression in specific mouse retinal ganglion cell types using two-photon imaging and MEA recordings.

The paper investigates regional adaptations in dendritic signal processing of sustained ON alpha retinal ganglion cells in the mouse retina, finding differences in signal integration between nasal and temporal regions that may aid in prey detection.

The paper introduces probabilistic solvers to quantify numerical uncertainty in neuroscience models, showing they reveal spike-time jitter and spike count changes with minimal computational cost.

The paper introduces a spline-based method for estimating neural receptive fields, showing improved performance over non-spline methods in both simulated and experimental data.

The paper shows that UV-cones in larval zebrafish eyes have distinct synaptic transfer functions based on their location, using a combination of imaging and modeling techniques.

This paper uses Bayesian inference to estimate parameters of retinal neuron models from imaging data and optimizes stimulus waveforms for retinal neuroprosthetics.

The paper identifies linear filters of retinal ganglion cells using a smooth electrical stimulus and an LNP model, showing diverse preferred stimuli in healthy and blind mouse retinas.