Ananya Gupta

This study identifies H19 as a PERK-regulated lncRNA that modulates UPR signaling and protects cells from ER stress-induced apoptosis in breast cancer.

This study shows that UPR reduces C/D box SnoRNP proteins, altering rRNA methylation and affecting translation fidelity through mechanisms like nonsense suppression and ribosome pausing.

The paper identifies DNA methylation biomarkers predictive of Type-2 diabetes in Asian populations and shows their utility in risk stratification.

This study shows that loss of Dicer1 in mouse fibroblasts reduces ER stress-induced apoptosis by altering UPR-related gene expression.