Antoine Anfray

This paper develops a minimally invasive thrombotic stroke model in mice that allows for reperfusion therapy and in vivo imaging, showing it produces reproducible infarcts and is ameliorated by tPA.

The paper investigates the relationship between nNOS neuron activity and vascular responses in the barrel cortex of awake mice, finding distinct temporal roles for different nNOS neuron subsets in neurovascular coupling.

This study identifies meningeal IL-17-producing T cells as a key driver of cognitive impairment in hypertension, showing their role in activating brain macrophages and suggesting therapeutic targets.