Jiaxing Wang

This study shows that oral Nicotinamide Riboside (NR) treatment protects retinal ganglion cells (RGCs) and optic nerve axons in DBA/2J mice, likely through increased retinal NAD+ levels, and also prevents iris depigmentation and delayed IOP elevation.

This study identifies Dnajc3 as a gene enhancing axon regeneration in mice by analyzing genomic variation across BXD strains and testing its effects on axon regeneration.

The paper identifies POU6F2 as a marker for a novel group of ON-OFF directionally selective retinal ganglion cells that are sensitive to glaucomatous injury.

The paper identifies a genomic locus on chromosome 8 associated with intraocular pressure (IOP) regulation in BXD RI mouse strains, with Cdh11 as the most likely candidate gene.

This study shows that genetic background affects optic nerve regeneration, with BXD strains showing significant variation in axonal regrowth.