NeuroscienceTranslational NeurodegenerationPeer-reviewed
N-terminally acetylated Met11-Tau: a new pathological truncated Tau species with functional relevance in Alzheimer Disease
Sarah Guedjdal, Coline Leghay, Maxime J. Derisbourg…·Malika Hamdane
This study identifies and characterizes a novel N-terminally acetylated Tau variant that accumulates in AD models and patients, exacerbates pathology, and is a potential therapeutic target.