Franck Martin

This study identifies and characterizes a novel N-terminally acetylated Tau variant that accumulates in AD models and patients, exacerbates pathology, and is a potential therapeutic target.

The paper identifies polyadenylated viral transcripts as the primary targets of the Drosophila siRNA pathway during RNA virus infection, rather than viral genomes.

The paper investigates how downstream RNA structures influence non-AUG translation initiation in eukaryotes and identifies genome-wide alternative initiation sites in humans.

The paper identifies SL1, a cis-acting RNA hairpin in SARS-CoV-2 5UTR, as a key element enabling viral translation despite NSP1-mediated host translation inhibition.