Author

Kévin Carvalho

InsermORCID 0000-0002-6432-7622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

David L BlumiD· 3 shared Luc BuéeiD· 3 shared Sabiha EddarkaouiiD· 2 shared Agathe LaunayiD· 1 shared Alexandre PelletieriD· 1 shared Anna Bogdanova· 1 shared Anne TailleuxiD· 1 shared Aude Deleau· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

David L BlumORCID

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Author profile →

3 papers

Recent·Most cited

N-terminally acetylated Met11-Tau: a new pathological truncated Tau species with functional relevance in Alzheimer Disease

Sarah Guedjdal, Coline Leghay, Maxime J. Derisbourg, Sabiha Eddarkaoui, Simon Lecerf, Florian Vermon, Raphaëlle Caillierez, Séverine Bégard, Claire Regost, Charlotte Laloux, Paulo J. da Costa, Kévin Carvalho, Giovanni Chiappetta, Yann Verdier, Valérie Buée‐Scherrer, , Malika Hamdane

This study identifies and characterizes a novel N-terminally acetylated Tau variant that accumulates in AD models and patients, exacerbates pathology, and is a potential therapeutic target.

Translational Neurodegeneration · Apr 27, 2026Peer-reviewedNeuroscience

Sex-dependent effects of maternal high-fat diet during lactation in adult THY-Tau22 mice offspring

Thibaut Gauvrit, Hamza Benderradji, Alexandre Pelletier, Kévin Carvalho, Soulaimane Aboulouard, Émilie Faivre, Estelle Chatelain, Hugo Cannafarina, Léna Labous, Agathe Launay, Marie Fourcot, Dimitri Kwiatkowski, Léna Chesnais, Emmanuelle Vallez, Tristan Cardon, , Didier Vieau

This study shows that maternal high-fat diet during lactation accelerates tauopathy in THY-Tau22 mice, with sex-dependent effects where males are more affected earlier than females.

Brain · Nov 3, 2025Peer-reviewedNeuroscience

A novel equilibrative nucleoside transporter 1 inhibitor alleviates Tau-mediated neurodegeneration

Ching‐Pang Chang, Ya‐Gin Chang, Pei‐Yun Chuang, Thi Ngoc Anh Nguyen, Fang-Yi Chou, Sin‐Jhong Cheng, Hui‐Mei Chen, Lee‐Way Jin, Kévin Carvalho, Vincent Huin, Luc Buée, David L Blum, Yung‐Feng Liao, Chun‐Jung Lin, Yijuang Chern

This study shows that inhibiting ENT1 with J4 reduces Tau-mediated neurodegeneration in a mouse model by improving energy homeostasis and mitigating immune responses.

bioRxiv · Oct 25, 2020 · PreprintNeuroscience