Author

Coline Leghay

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Destée· 1 shared Alberto Bergareche‐Yarza· 1 shared Amélie Vizeneux· 1 shared Ana Vinagre‐AragóniD· 1 shared Belén FernándeziD· 1 shared Camille Calvez· 1 shared Charlotte LalouxiD· 1 shared Claire RegostiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

A. Destée

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

N-terminally acetylated Met11-Tau: a new pathological truncated Tau species with functional relevance in Alzheimer Disease

Sarah Guedjdal, Coline Leghay, Maxime J. Derisbourg, Sabiha Eddarkaoui, Simon Lecerf, Florian Vermon, Raphaëlle Caillierez, Séverine Bégard, Claire Regost, Charlotte Laloux, Paulo J. da Costa, Kévin Carvalho, Giovanni Chiappetta, Yann Verdier, Valérie Buée‐Scherrer, , Malika Hamdane

This study identifies and characterizes a novel N-terminally acetylated Tau variant that accumulates in AD models and patients, exacerbates pathology, and is a potential therapeutic target.

Translational Neurodegeneration · Apr 27, 2026Peer-reviewedNeuroscience

A potential patient stratification biomarker for Parkinson's disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells

Yahaira Naaldijk, Belén Fernández, Rachel Fasiczka, Elena Fdez, Coline Leghay, Ioana M. Croitoru, John B. Kwok, Yanisse Boulesnane, Amélie Vizeneux, Eugénie Mutez, Camille Calvez, A. Destée, Jean‐Marc Taymans, Ana Vinagre‐Aragón, Alberto Bergareche‐Yarza, , Sabine Hilfiker

Peripheral blood-derived cells can be employed to stratify Parkinson's disease patients most likely to respond to LRRK2-related therapeutics.

bioRxiv · Apr 11, 2023 · PreprintNeuroscience