Di Zhang

This study uses single-nucleus and spatial ATAC-seq to uncover epigenomic heterogeneity and spatial niches in non-functional pancreatic neuroendocrine tumors.

The paper identifies differentially expressed proteins in human epileptic brain tissue and validates their roles in epileptogenesis through experimental validation.

The paper quantifies translational regulation in E. coli across 12 conditions, revealing gene-specific and cross-condition variability in translation efficiency.

The paper shows that gene deletion effects can be split into clustered and distributed effects, with only clustered effects aligning with known biochemical functions and distributed effects being evolutionarily decoupled.