Author

Mengdi Liu

Hebei UniversityORCID 0000-0001-6499-3126Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Bin ZhouiD· 1 shared Chunguang HaniD· 1 shared Chunyu ZhouiD· 1 shared Di ZhangiD· 1 shared Guan YangiD· 1 shared Jian Wang· 1 shared Jing YangiD· 1 shared Jing‐Dong J. HaniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Bin ZhouORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintJun 14, 2026

Cardiomyocytes Undergo a Mesenchymal-Like Fate Transition in Myocardial Fibrosis

Tianle Wang, Chunyu Zhou, Mengdi Liu…·Xiao Yi Yang

This study shows that cardiomyocytes can transition to a mesenchymal-like fate during myocardial fibrosis, regulated by HGS and ALDH1A2, contributing to fibrosis and calcification.

DOI 10.64898/2026.06.10.731493

humanmouse

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GeneticsNational Science ReviewPeer-reviewedApr 22, 2020

Decoupling gene knockout effects from gene functions by evolutionary analyses

Li Liu, Mengdi Liu, Di Zhang…·Xionglei He

The paper shows that gene deletion effects can be split into clustered and distributed effects, with only clustered effects aligning with known biochemical functions and distributed effects being evolutionarily decoupled.

7 citations

yeaststatistical model

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