Fu Gao

This study introduces spatial-GPT, a platform for spatial glycan, protein, and transcriptome profiling in human liver tissues, revealing glyco-codes that define disease states and progression.

This study identifies ECM-dominant cardiovascular diseases as driven by coordinated CDKN1A and CDKN2A senescence programs in fibroblasts and shows senolytic treatments improve cardiac function.

This study maps age-related cellular senescence in human lymph nodes, identifying senescence markers and spatial shifts in germinal center B cells.

The paper identifies a conserved activated valvular interstitial cell population across species and disease types that drives myxomatous mitral valve degeneration.

This study uses single-nucleus and spatial ATAC-seq to uncover epigenomic heterogeneity and spatial niches in non-functional pancreatic neuroendocrine tumors.