Hailin Zhang

The cation channel mechanisms of subthreshold inward depolarizing currents in the VTA dopaminergic neurons and their roles in the chronic-stress-induced depression-like behavior

This study identifies NALCN and TRPC6 cation channels as mediators of subthreshold inward depolarizing currents in VTA DA neurons and links their down-regulation to depression-like behavior in chronic stress.

Insights into Human Epileptogenesis with Proteomic Profiling

The paper identifies differentially expressed proteins in human epileptic brain tissue and validates their roles in epileptogenesis through experimental validation.

Dorsal root ganglia control nociceptive input to the central nervous system

The paper demonstrates that dorsal root ganglia (DRG) filter nociceptive signals through axonal t-junctions, with GABAergic cells enhancing this filtering and reducing pain hypersensitivity in models of inflammation and neuropathy.

Transcriptional regulation of voltage-gated sodium channels contributes to GM-CSF induced pain

This study identifies GM-CSF's role in bone cancer pain by upregulating voltage-gated sodium channels via Jak2/Stat3 signaling in DRG neurons.