Author

Jamie S. Depelteau

Leiden UniversityORCID 0000-0001-8983-2855Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ariane BriegeliD· 3 shared Susanne BrenzingeriD· 2 shared Adam Sidi MabroukiD· 1 shared Annabel Kempff· 1 shared Annemarie H. MeijeriD· 1 shared Bart W. BardoeliD· 1 shared C. Keith CassidyiD· 1 shared Chiara FoiniiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMolecular Biology

Ariane BriegelORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 3, 2026

Identification of a C3b-specific nanobody that does not bind C3 and blocks alternative pathway convertases

Eva M. Struijf, Bart W. Bardoel, Joanne E. van Keulen…·Jamie S. Depelteau

This study identifies a C3b-specific nanobody that binds C3b but not C3, and inhibits the alternative pathway convertases of the complement system.

DOI 10.64898/2026.08.30.748118

humanprotein structure

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MicrobiologyMicrobiology SpectrumPeer-reviewedMay 4, 2026

ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae

Adam Sidi Mabrouk, Jamie S. Depelteau, Chiara Foini…·Ariane Briegel

This study shows that ICP1 bacteriophage treatment effectively clears Vibrio cholerae from zebrafish larvae intestines, independent of microbiome composition.

2 citationstop 3%

zebrafishimaging

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Molecular BiologyCommunications BiologyPeer-reviewedJan 11, 2022

UVC inactivation of pathogenic samples suitable for cryoEM analysis

Jamie S. Depelteau, Ludovic L. R. Renault, Nynke Althof…·Ariane Briegel

This study shows that UVC irradiation at cryogenic temperatures can inactivate pathogens without damaging their structure, making them suitable for cryo-EM analysis.

10 citations

bacteria (other)virus

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Molecular BiologyMicroscopy and MicroanalysisPeer-reviewedJan 18, 2018

An open-source cryo-storage solution

Eveline Ultee, Fred Schenkel, Wen Jing Yang…·Ariane Briegel

The paper presents an open-source cryo-storage system to improve sample storage efficiency and organization in cryo-EM laboratories.

1 citation

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