Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia
Ping Wang, Zhonghui Tang, Byoungkoo Lee…·Yijun Ruan
This study investigates how PML/RARα alters chromatin topology and transcription in APL cells, revealing its role in repressing myeloid differentiation genes.