Roshan Cools

This study investigates how state anxiety affects task disengagement in relation to trait anxiety, finding that trait anxiety reduces the impact of state anxiety on task disengagement.

This study investigates how dopamine modulates striatal activity during working memory output-gating using fMRI and finds that sulpiride alters striatal activity and reduces neural stimulus selectivity in visual cortex, affecting task performance.

The paper validates the REACT method for isolating dopamine-specific effects of methylphenidate on brain function using fMRI and PET data.

This study shows dopamine enhances both reinforcement learning and working memory, reduces effort costs, and highlights the need to account for its effects on working memory when studying reinforcement learning.

This study compares the subjective effort costs of distractor resistance and flexible updating in working memory tasks, finding that distractor resistance is more effortful.

The study investigates how the brain generalizes abstract linguistic rules to form novel meanings, finding that a frontoparietal network, not the medial prefrontal-hippocampal network, supports this process.

This study investigates the relationship between inflammatory tone and reinforcement learning in Parkinson's disease but finds no significant associations.

This study examines the impact of an 8-week mindful eating intervention on neural reward anticipation responses in striatum and midbrain, finding reduced midbrain responses but no effect on striatum or eating behavior.

The paper investigates whether simple trait measures correlate with striatal dopamine synthesis capacity and finds no significant correlations.

The paper tests the Learning Progress Motivation theory by showing that task engagement and cognitive effort are mediated by dynamic performance changes in challenging tasks.

The paper investigates how the hippocampal formation represents different types of relational information by analyzing fMRI data to show distinct semantic and statistical maps.

The paper shows humans estimate environmental controllability by comparing actor and spectator models, with stress reducing perceived control and increasing reliance on the spectator model.

The paper examines how striatal BOLD and midfrontal theta power relate to motivation for action during a Go/NoGo task, finding distinct roles for early and late theta components in reflecting motivational biases and behavioral responses.

The paper shows that cortical regions encode biased prediction errors before subcortical regions during action-outcome learning.

The paper investigates how the framing of social advice influences decision-making, finding that appetitive framing increases trust and learning compared to aversive framing.

The paper links striatal dopamine synthesis capacity to smartphone social activity using PET scans and behavioral data from healthy adults.

This study investigates whether dopamine synthesis capacity predicts individual variation in curiosity by analyzing behavioral and neuroimaging data.

The study replicates a previous finding that reward effects on cognitive control depend on dopamine synthesis capacity but fails to find a correlation in a larger sample using a different radiotracer.

This study shows methylphenidate increases preference for mental labor over leisure, especially in individuals with higher baseline striatal dopamine.

The paper shows methylphenidate enhances cognitive effort by altering the benefit-to-cost ratio of cognitive work through striatal dopamine signaling.

This study investigates how pseudo-reward prediction errors in the striatum influence value-based decision-making, finding that they bias choices even without actual reward.

This study investigates how catecholamines modulate avoidance of cognitive control during task switching, finding that methylphenidate increases avoidance in individuals with higher trait impulsivity.

The paper tests whether social and individual learning differ due to social nature or directness using a catecholamine challenge, finding distinct effects on direct and indirect learning but not on social versus non-social learning.

The paper investigates the relationship between spontaneous eye blink rate and striatal dopamine synthesis capacity using PET imaging and finds no positive correlation, suggesting caution in interpreting sEBR as a proxy for dopamine function.

This study investigates how dopamine D2/D3 receptor antagonism affects probability weighting during risky decision-making in healthy individuals and pathological gamblers.

This study investigates the causal effects of transcranial magnetic stimulation on striatal processing of motivation, cognition, and action by targeting different frontal brain regions.

This study shows that food labels influence implicit motivation and neural responses to drinks, even when the drinks are objectively identical.

The paper investigates how outcome uncertainty and expected reward influence curiosity, finding that uncertainty drives curiosity and is linked to parietal and insular cortex activity.

This study finds that orexin-deficient narcolepsy patients show enhanced ventral medial prefrontal cortex responses to food words, which predicts increased snack intake.

This study shows that Parkinson’s disease patients with depression have impaired reward and punishment reversal learning and reduced striatal BOLD signals.