Author

Sylvia M. Cruz

University of California, IrvineORCID 0000-0001-9007-6639Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Claire C. CheniD· 1 shared Claudia A. BenaventeiD· 1 shared Jie WuiD· 1 shared Loredana ZocchiiD· 1 shared Marina Suarez-Pizarro· 1 shared Parker J. Smith· 1 shared Roberto TinocoiD· 1 shared Susie SuhiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Claire C. ChenORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMar 2, 2025

UHRF1 is critical for tumor-promoting inflammation and tumorigenesis in retinoblastoma

Yijun Gu, Marina Suarez-Pizarro, Claire C. Chen…·Claudia A. Benavente

This study shows that UHRF1 is essential for retinoblastoma progression by promoting oncogenic transcription, chromatin accessibility, and immune microenvironment shaping, but not tumor initiation.

2 citations

mousebulk RNA-seq

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