Melanie Jane Bailey

This study optimizes MALDI MSI conditions on PEN substrates for small molecule analysis, enabling effective same-section multimodal workflows.

The paper develops and applies complementary microflow HILIC and ion pair LC-MS methods to analyze single-cell metabolomics in a tuberculosis macrophage model, revealing infection-associated metabolic changes and a distinct bystander phenotype.

This paper introduces a nanoflow ion-pairing LC-MS method for ultra-low-input polar metabolomics and isotope tracing, showing improved sensitivity and retention for metabolites.

The paper introduces a capillary-based subcellular sampling method combined with LC-MS to analyze stress granule proteomes in single cells, identifying 405 high-confidence proteins with minimal cytosolic contamination.

This study quantifies carbon-nitrogen and nitrogen metabolism in mycobacteria using Bayesian multi-model-based 13C15N metabolic flux analysis, identifying glutamate as a central metabolic node.