Katharina Nöh

Does specific membrane surface area constrain Escherichia coli energy spillage and therefore aerobic and anaerobic growth rates?

This study quantifies how specific membrane surface area (sMSA) constrains Escherichia coli growth rates and energy metabolism across aerobic and anaerobic conditions.

Multi-omic data fusion reveals the in vivo enzyme kinetics of Vibrio natriegens at the genome-scale

This study measures in vivo enzyme turnover numbers in Vibrio natriegens using multi-omic data fusion, revealing enzymes are 14-fold faster than E. coli and showing machine learning underestimates these kinetics.

hopsy - a methods marketplace for convex polytope sampling in Python

hopsy provides a Python platform for accessing Markov chain Monte Carlo sampling algorithms for convex polytopes, enabling collaboration between developers and users.

MooViE - Engine for single-view visual analysis of multivariate data

MooViE provides a visual analysis tool for exploring multivariate data, offering a single-view visualization to extract insights across various life science applications.

ObiWan-Microbi: OMERO-based integrated workflow for annotating microbes in the cloud

ObiWan-Microbi provides a cloud-based platform for semi-automated image annotation in microfluidic live-cell imaging using deep learning segmentation.

microbeSEG: A deep learning software tool with OMERO data management for efficient and accurate cell segmentation

microbeSEG provides a deep learning tool for automated cell segmentation in microbial cultures, achieving accurate results within 45 minutes of user time.

CHRRT: boosting coordinate hit-and-run with rounding by thinning

The paper introduces CHRRT, a modified Coordinate Hit-and-Run with Rounding algorithm that uses thinning to improve computational efficiency for sampling convex polytopes, achieving up to three orders of magnitude faster effective sample size per time.

Bayesian multi-model-based 13C15N-metabolic flux analysis quantifies carbon-nitrogen metabolism in mycobacteria

This study quantifies carbon-nitrogen and nitrogen metabolism in mycobacteria using Bayesian multi-model-based 13C15N metabolic flux analysis, identifying glutamate as a central metabolic node.

CellSium - Versatile Cell Simulator for Microcolony Ground Truth Generation

CellSium generates synthetic microcolony images for training deep learning segmentation models in microfluidic live-cell imaging.