Author

Xianju Bi

Center for Life SciencesORCID 0000-0001-9061-2622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ahu Turkoz· 1 shared Anders MälarstigiD· 1 shared Brad T. Townsley· 1 shared Brian S. EganiD· 1 shared Chames KermiiD· 1 shared Clifford R. Restaino· 1 shared Dörte SchlesingeriD· 1 shared Ge Zhan· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ahu Turkoz

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2 papers

Recent·Most cited

Cancer BiologyeLifePeer-reviewedOct 13, 2025

KDM5 demethylases suppress R-loop-mediated viral mimicry and DNA damage in breast cancer cells

Lena Lau, Kurt Henderson, Ahu Turkoz…·Marie Classon

This study shows that KDM5 demethylases suppress R-loop formation in breast cancer cells, reducing DNA damage and enhancing immune-related gene expression without affecting normal cells.

DOI 10.7554/elife.106249.3

humanDNA methylation

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GenomicsbioRxivPreprintOct 13, 2019

L1 and B1 repeats blueprint the spatial organization of chromatin

J. Yuyang Lu, Lei Chang, Tong Li…·Xiaohua Shen

This study identifies L1 and B1 retrotransposons as key elements shaping the 3D chromatin structure through spatial compartmentalization in human and mouse cells.

7 citations

humanmouse

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