Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in Systemic Lupus Erythematosus
Minji Ai, Xian Zhou, Michele Carrer, Paymaan Jafar‐Nejad, Yanfeng Li, Naomi M. Gades, Mariam P. Alexander, Mario Alejandro Bautista-Vargas, Alí Duarte‐García, Hu Zeng
This study investigates the role of mTORC2 in SLE and shows that targeting mTORC2 reduces immunopathology in both mouse models and human PBMCs.
Rheumatology · Dec 3, 2024Peer-reviewedImmunology