Xian Zhou

This study shows KH0 and KH1 domains of FMR1 work together in m6A binding and phase separation, linking these processes to Fragile X Syndrome pathology.

This study investigates the role of mTORC2 in SLE and shows that targeting mTORC2 reduces immunopathology in both mouse models and human PBMCs.

This study shows that Rag-GTPases regulate B cell metabolism and immunity by restraining TFEB/TFE3 to maintain mitochondrial fitness and support T-independent humoral immunity.

This study shows that PP2A catalytic subunit alpha is essential for CD8+ T cell homeostasis and anti-bacterial responses, with Bcl2 rescue limited to spleen.

This study compares the anti-inflammatory effects of andrographolide to NSAIDs, finding it more effective in inhibiting cytokine release and NF-κB activation in macrophage cells.