Author

Hu Zeng

Mayo ClinicORCID 0000-0002-9909-7732Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Yanfeng Li· 3 shared Meilu LiiD· 2 shared Xingxing ZhuiD· 2 shared Aditya Bhagwate· 1 shared Alí Duarte‐GarcíaiD· 1 shared Haidong DongiD· 1 shared Jean‐Pierre KocheriD· 1 shared Junwen WangiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersImmunology

Yanfeng Li

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ACLY integrates metabolism and chromatin accessibility to enable B Cell activation and humoral immunity

Meilu Li, Zhiqiang Zhang, Xian Zhou, Yanfeng Li, Xingxing Zhu, Aditya Bhagwate, Nagaswaroop Kengunte Nagaraj, Hu Zeng

This study shows ACLY links metabolism to chromatin accessibility in B cells, essential for activation and humoral immunity.

bioRxiv · May 27, 2026 · PreprintImmunology

Immunopipe: A comprehensive and flexible scRNA-seq and scTCR-seq data analysis pipeline

Panwen Wang, Yue Yu, Haidong Dong, Shuwen Zhang, Zhifu Sun, Hu Zeng, Patrizia Mondello, Jean‐Pierre Kocher, Junwen Wang, Yan W. Asmann, Yi Lin, Ying Li

Immunopipe provides a flexible pipeline for integrated analysis of scRNA-seq and scTCR-seq data to enhance understanding of T-cell immunity and immunotherapy.

NAR Genomics and Bioinformatics · Mar 29, 2025Peer-reviewedBioinformatics

Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in Systemic Lupus Erythematosus

Minji Ai, Xian Zhou, Michele Carrer, Paymaan Jafar‐Nejad, Yanfeng Li, Naomi M. Gades, Mariam P. Alexander, Mario Alejandro Bautista-Vargas, Alí Duarte‐García, Hu Zeng

This study investigates the role of mTORC2 in SLE and shows that targeting mTORC2 reduces immunopathology in both mouse models and human PBMCs.

Rheumatology · Dec 3, 2024Peer-reviewedImmunology

CPT2 mediated fatty acid oxidation is dispensable for humoral immunity

Meilu Li, Xian Zhou, Xingxing Zhu, Yanfeng Li, Taro Hitosugi, Yuzhen Li, Hu Zeng

This study shows that CPT2-mediated fatty acid oxidation is not essential for humoral immunity in mice, as CPT2 deficiency does not impair B cell development, activation, or antibody production.

The Journal of Immunology · Sep 11, 2024Peer-reviewedImmunology