BiochemistrybioRxivPreprint
Structural basis of underwound DNA topology bearing PAM-mutant recognition by AtCas9
Min Duan, Bing Meng, Lei Zhou…·Ying Zhang
This study reveals how DNA topology affects PAM recognition by AtCas9 through cryo-EM structures of underwound DNA complexes.
DOI 10.64898/2026.01.30.702744