Cancer BiologybioRxivPreprint
SRRM1 coordinates an alternative splicing program that promotes expression of oncogenic protein isoforms.
Kamal Othman, Lauren Viola, Hira Fatima…·C. Jane McGlade
This study identifies SRRM1 as a splicing regulator that promotes oncogenic NUMB isoforms and other cancer-related splicing events, leading to increased tumorigenic properties in multiple cancer cell lines.
DOI 10.1101/2025.08.20.671097