Author

Emmanuel Lemichez

Centre National de la Recherche ScientifiqueORCID 0000-0001-9080-7761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:mixed model· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Amaury VaysseiD· 1 shared Amel MettouchiiD· 1 shared Anna E. YoshidaiD· 1 shared Caroline StefaniiD· 1 shared Christine Rasetti‐EscargueiliD· 1 shared Diane LetourneuriD· 1 shared Emma BergsteniD· 1 shared Giulia NigroiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Amaury VaysseORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 2, 2025

The E. coli CNF1 toxin induces fetal reprogramming of intestinal stem cells and a serrated colorectal cancer transcriptional signature in organoids

Diane Letourneur, Emma Bergsten, Nathan Raynaud…·Amel Mettouchi

This study shows that the E. coli CNF1 toxin reprograms intestinal stem cells in organoids to a fetal-like state, inducing a serrated colorectal cancer transcriptional signature.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceToxinsPeer-reviewedSep 17, 2022

In silico conformational features of botulinum toxins A1 and E1 according to the intraluminal acidification

Grazia Cottone, Letizia Chiodo, Luca Maragliano…·Thérèse E. Malliavin

This study uses molecular dynamics simulations to analyze conformational changes in botulinum toxins A1 and E1 under different pH conditions, revealing domain movements and structural dynamics.

4 citations

protein structuremixed model

𝕏 PostBluesky