Author

Giulia Nigro

InsermORCID 0000-0002-1014-7394Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Iradj SobhaniiD· 2 shared A. Försti· 1 shared Alice CarrieriD· 1 shared Amaury VaysseiD· 1 shared Amel MettouchiiD· 1 shared Anna E. YoshidaiD· 1 shared ANR. Wewer· 1 shared Audrey VincentiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

Iradj SobhaniORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ILC3s are Required for Enterocyte Homeostasis to Food Intake

Emelyne Lécuyer, Fabian Guendel, Sascha Cording, Giulia Nigro, Jasna Medvedovic, Sophie Dulauroy, Helena Moguel-Houssin, Marion Rincel, Benoît Chassaing, Francina Langa Vives, François Déjardin, Gérard Eberl

This study shows that ILC3s prevent post-prandial inflammation by regulating enterocyte metabolism during food intake.

bioRxiv · Apr 22, 2026 · PreprintImmunology

A crypt-operating DNA repair checkpoint for uncoupling regeneration and tumorigenesis

Richard Ruez, K. Radulovic, JJ Martinez-Torres, Olivier Boulard, Mound. Abdallah, Thomas Paz del Socorro, Giulia Nigro, Marion Seillier, Ghaffar Muharram, JJ Martinez-Garcia, François Gerbe, Emilie Floquet, Isabelle VAN SEUNINGEN, Alice Carrier, Philippe Jay, , Mathias Chamaillard

This study identifies Nlrp6 as a regulator of DNA repair and epithelial regeneration in intestinal crypts, linking DNA damage responses to colorectal cancer progression.

bioRxiv · Mar 2, 2026 · PreprintCell Biology

The E. coli CNF1 toxin induces fetal reprogramming of intestinal stem cells and a serrated colorectal cancer transcriptional signature in organoids

Diane Letourneur, Emma Bergsten, Nathan Raynaud, Juliette Mondy, Giulia Nigro, Landry Laure Tsoumtsa, Amaury Vaysse, Stéphane Descorps‐Declère, Anna E. Yoshida, Caroline Stefani, Iradj Sobhani, Emmanuel Lemichez, Amel Mettouchi

This study shows that the E. coli CNF1 toxin reprograms intestinal stem cells in organoids to a fetal-like state, inducing a serrated colorectal cancer transcriptional signature.

bioRxiv · Oct 2, 2025 · PreprintCancer Biology

A virus-encoded microRNA contributes to evade innate immune response during SARS-CoV-2 infection

Meetali Singh, Maxime Chazal, Piergiuseppe Quarato, Loan Bourdon, Christophe Malabat, Thomas Vallet, Marco Vignuzzi, Sylvie van der Werf, Sylvie Behillil, Flora Donati, Nathalie Sauvonnet, Giulia Nigro, Maryline Bourgine, Nolwenn Jouvenet, Germano Cecere

The paper identifies a virus-encoded microRNA in SARS-CoV-2 that targets interferon-stimulated genes to suppress the host immune response.

EMBO Reports · Dec 16, 2021Peer-reviewedMolecular Biology