Author

Emma Bergsten

Centre National de la Recherche ScientifiqueORCID 0000-0001-9486-3103Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Amaury VaysseiD· 2 shared Iradj SobhaniiD· 2 shared Amel MettouchiiD· 1 shared Anna E. YoshidaiD· 1 shared Aurélien AmiotiD· 1 shared Caroline BarauiD· 1 shared Caroline StefaniiD· 1 shared Cécile Charpy· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Amaury VaysseORCID

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2 papers

Recent·Most cited

The E. coli CNF1 toxin induces fetal reprogramming of intestinal stem cells and a serrated colorectal cancer transcriptional signature in organoids

Diane Letourneur, Emma Bergsten, Nathan Raynaud, Juliette Mondy, Giulia Nigro, Landry Laure Tsoumtsa, Amaury Vaysse, Stéphane Descorps‐Declère, Anna E. Yoshida, Caroline Stefani, Iradj Sobhani, Emmanuel Lemichez, Amel Mettouchi

This study shows that the E. coli CNF1 toxin reprograms intestinal stem cells in organoids to a fetal-like state, inducing a serrated colorectal cancer transcriptional signature.

bioRxiv · Oct 2, 2025 · PreprintCancer Biology

Poor prognosis in IBD-complicated colon cancer through gut dysbiosis-related immune response failure

Iradj Sobhani, Nilmara de Oliveira Alves, Mohammad Sadeghi, Cécile Charpy, Emma Bergsten, Aurélien Amiot, Caroline Barau, Francesco Brunetti, Amaury Vaysse, Christophe Tournigand, Mathias Chamaillard, Khashayarsha Khazaie, Denis Mestivier

This study identifies poor prognosis in IBD-related colon cancer due to gut dysbiosis and immune response failure, linked to microbial imbalance and altered gene expression.

bioRxiv · Mar 25, 2025 · PreprintImmunology