Author

Ernesto Criado-Hidalgo

California Institute of TechnologyORCID 0000-0001-9086-9129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Mikhail G. ShapiroiD· 3 shared Ann LiuiD· 2 shared Hongyi LiiD· 2 shared M SwiftiD· 2 shared Akanksha YadaviD· 1 shared Ali FarooqiD· 1 shared Bill LingiD· 1 shared Claire RabutiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBioengineering

Mikhail G. ShapiroORCID

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3 papers

Recent·Most cited

In vivo spatial coordination with synthetic paracrine signaling

Kaiwen Luo, Yitong Ma, Hongyi Li, Hengyu Li, Mengziang Lei, M Swift, Nathan F. Dalleska, Ali Farooq, Ernesto Criado-Hidalgo, Ann Liu, Mikhail G. Shapiro, Michael B. Elowitz

The paper develops a synthetic paracrine signaling system using auxin to enable spatially restricted multicellular responses in mouse xenografts.

bioRxiv · Aug 27, 2026 · PreprintSynthetic Biology

A modular method for rapidly prototyping targeted gas vesicle protein nanoparticles

Reid Vassallo, Bill Ling, Ernesto Criado-Hidalgo, Nicole Robinson, Erik Schrunk, Ann Liu, George H. Daghlian, Hongyi Li, M Swift, Dhiraj Mannar, Dina Malounda, S. Larry Goldenberg, Septimiu E. Salcudean, Mikhail G. Shapiro, Peter C. Black, Michael Cox

The paper describes a modular method to create targeted gas vesicle protein nanoparticles using His-tagged antibody fragments and Ni-NTA functionalization, validated for PSMA targeting.

Bioconjugate Chemistry · Jan 19, 2026Peer-reviewedBioengineering

Ultrasound imaging of in situ transcriptional activity in opaque tissue

Shirin Shivaei, Kathy Y.M. Cheung, Akanksha Yadav, Isabella U. Hurvitz, Sunho Lee, Julio Revilla, Claire Rabut, Ernesto Criado-Hidalgo, Raymond J. Zhang, Mikhail G. Shapiro

This paper develops a system to image in situ transcriptional activity in opaque tissues using ultrasound and acoustic reporter genes, demonstrating long-term tracking of gene expression in the mouse brain.

bioRxiv · Jul 6, 2025 · PreprintBioengineering