Yitong Ma

The paper develops a synthetic paracrine signaling system using auxin to enable spatially restricted multicellular responses in mouse xenografts.

The paper identifies RASGRP3 as a context-specific essential gene in uveal melanoma and develops a CRISPR-Cas13d RNA-targeting therapeutic that selectively eliminates uveal melanoma cells.

This study introduces CRISPR-TO to manipulate RNA localization in neurons, showing it affects neurite outgrowth and axonal regeneration.

EasyFlow provides an open-source, user-friendly flow cytometry analysis tool with a GUI, accessible without coding knowledge and supporting both Matlab and Python.

The paper constructs promoters with varying CpG content to study how CpG density affects silencing rate via DNMT recruitment, finding a strong correlation and identifying a key CpG site.

This paper designs a synthetic mammalian circuit using auxin for population control, showing it limits growth more robustly than non-paradoxical designs.