Author

Kristina Kronborg

University of CopenhagenORCID 0000-0001-9087-0752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Yong Everett ZhangiD· 2 shared Ditlev Egeskov BroderseniD· 1 shared Kenn GerdesiD· 1 shared Luokai WangiD· 1 shared Muriel Leandra SchicketanziD· 1 shared René L. BærentseniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

Yong Everett ZhangORCID

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2 papers

Recent·Most cited

Phage portal proteins counteract stringent-response-mediated restriction

Kristina Kronborg, Luokai Wang, Muriel Leandra Schicketanz, Kenn Gerdes, Yong Everett Zhang

This study identifies phage portal proteins as factors that counteract bacterial stringent response by inhibiting alarmone synthetases, revealing a conserved viral strategy to overcome host stress physiology.

Nature Communications · Jul 11, 2026Peer-reviewedMicrobiology

Catalytic Mechanism and Differential Alarmone Regulation of a Conserved Stringent Nucleosidase

René L. Bærentsen, Kristina Kronborg, Ditlev Egeskov Brodersen, Yong Everett Zhang

This study investigates how the alarmones ppGpp and pppGpp differentially regulate the nucleosidase PpnN in E. coli, revealing its role in bacterial survival under antibiotic stress and uncovering a conserved catalytic mechanism shared with plant cytokinin signaling proteins.

Structure · Nov 5, 2025Peer-reviewedBiochemistry