Author

Xiangbin Ruan

University of ChicagoORCID 0000-0002-6895-2070Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:statistical model· 1

Frequent Co-Authors

Xiaochang ZhangiD· 2 shared Aileen KauffmaniD· 1 shared Bin YiniD· 1 shared Boqin Qiang· 1 shared Bowei KangiD· 1 shared Chang WeniD· 1 shared Chuan HeiD· 1 shared Elizabeth TsengiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Xiaochang ZhangORCID

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3 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedApr 13, 2026

YTHDF1 mediates translational control by m6A mRNA methylation in adaptation to environmental challenges

Zhuoyue Shi, Kailong Wen, Wenqin Fu…·Xiaoxi Zhuang

This study shows that YTHDF1 mediates m6A mRNA methylation in neuronal adaptation to environmental challenges, with distinct roles in D1 and D2 neurons.

3 citations

mouseexperimental assay

Developmental BiologyJournal of NeurosciencePeer-reviewedNov 12, 2024

Cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex

Xiangbin Ruan, Kaining Hu, Yalan Yang…·Xiaochang Zhang

The paper identifies cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex, showing differential splicing impacts on neuronal migration and differentiation.

2 citations

mousebulk RNA-seq

NeuroscienceCell ReportsPeer-reviewedJul 1, 2019

COMPASS Family Histone Methyltransferase ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signalling

Liang Li, Xiangbin Ruan, Chang Wen…·Xiaozhong Peng

This study shows that ASH2L regulates Wnt-β-catenin signalling in NPCs, affecting their proliferation and neuronal positioning during corticogenesis.

34 citations

mouseexperimental assay