Cancer BiologyDisease Models & MechanismsPeer-reviewed
Macrophages drive the earliest anti-tumoral response to BCG therapy by directly killing bladder cancer through TNF signaling
Mayra Fernanda Martínez-López, Cátia Rebelo de Almeida, Márcia Fontes…·Rita Fior
This study identifies macrophages as key drivers of BCG therapy's anti-tumoral effect through direct TNF-mediated cancer cell killing, independent of adaptive immunity.
18 citations