Single-locus chromatin memory enables flexible spatial fate specification in the Drosophila visual system
Yen‐Chung Chen, Sophia Nielsen, Ben Jiwon Choi, Asif Bakshi, Rose Coyne, Mehmet Neset Özel, Claude Desplan
The paper shows that single-locus chromatin memory in Drosophila medulla progenitors allows spatial identity to be faithfully executed or flexibly bypassed during neuronal fate specification.
bioRxiv · Aug 21, 2026 · PreprintDevelopmental Biology