Bronwyn A. Lucas

This paper introduces Nilas, a cryo-FIB milling strategy that minimizes damage and improves resolution for in situ structural biology.

Leopard-EM accelerates in situ cryo-EM analysis by providing a modular 2DTM framework that improves ribosome detection and enables single-molecule resolution of rotation states.

This paper introduces a new statistical metric, 2DTM p-value, to improve target detection in cryo-EM by combining SNR and z-score, showing better performance for complex targets.