Shihuan Kuang

The paper identifies a senescent-like muscle stem cell subpopulation that drives muscle regeneration through secretory activity and cell communication.

This study shows that inhibiting Pten in adipocytes improves metabolic health by increasing lipid storage, preserving function, and reducing inflammation.

This study identifies chondrolectin as a regulator of satellite cell localization and regenerative function in mice through single-cell RNA-seq and knockout models.

This study identifies NRMLncR, a myocyte-enriched lncRNA, as a regulator of myogenesis in mouse, showing it enhances differentiation through interactions with MyoD/MyoG and CELF1.

This study shows that 12/15-LOX is essential for inflammation resolution and skeletal muscle regeneration by regulating lipid mediators and myogenic progenitor cell function.

This study shows PRMT5 links lipid metabolism to skeletal muscle function by regulating SREBP1a and ATGL through epigenetic mechanisms.

This study shows that PTEN inhibition reduces muscle degeneration and improves function in mdx mice, a model of Duchenne Muscular Dystrophy.