Xiaoxin X. Wang

This study shows that deleting ERRγ in podocytes accelerates aging-related kidney disease by impairing mitochondrial function and increasing albuminuria.

This study shows that Finerenone reduces kidney disease in mice by improving mitochondrial function, lowering lipid accumulation, and reducing inflammation.

This study uses a 3D endothelium-on-a-chip model to show that Cx43-dependent glycolytic shifts contribute to endothelial barrier dysfunction in diabetic kidney disease.

This study shows that NAD+ supplementation protects against CKD in Alport syndrome by restoring FAO in proximal tubule cells and reveals sex differences in transcriptional responses.