NeurosciencebioRxivPreprint
Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes
Madeline G. Andrews, Tanzila Mukhtar, Ugomma C. Eze…·Arnold R. Kriegstein
In primary human cortical tissue and stem cell-derived organoids, SARS-CoV-2 infects astrocytes almost exclusively, apparently through DPP4 rather than ACE2, leaving them reactive and stressed.
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