Author

Chinyere Agbaegbu Iweka

Stanford MedicineORCID 0000-0001-9228-2436Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Eran BlacheriD· 2 shared Katrin I. AndreassoniD· 2 shared Aarooran Sivakumaran DurairajiD· 1 shared Abigail J. ZuckermaniD· 1 shared Aisling M. ChaneyiD· 1 shared Amira Latif‐HernandeziD· 1 shared Caitlin P. MencioiD· 1 shared Congcong Wang· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Eran BlacherORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 5, 2024

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease models

Edward N. Wilson, Congcong Wang, Michelle S. Swarovski…·Katrin I. Andreasson

This study shows that TREM1 deficiency prevents age-related myeloid metabolic changes and cognitive decline in Alzheimer's disease models.

DOI 10.1101/2024.03.05.583562

𝕏 PostBluesky

NeuroscienceJournal of NeuroinflammationPeer-reviewedFeb 24, 2023

Myeloid deficiency of the intrinsic clock protein Bmal1 accelerates cognitive aging by disrupting microglial synaptic pruning

Chinyere Agbaegbu Iweka, Erica M. Seigneur, Amira Latif‐Hernandez…·Katrin I. Andreasson

This study shows that Bmal1 deficiency in myeloid cells disrupts microglial synaptic pruning, accelerates cognitive aging, and affects sleep-wake cycles in mice.

42 citationstop 5%

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 2, 2019

The lipid phosphatase-like protein PLPPR1 increases cell adhesion by modulating RhoA/Rac1 activity

Chinyere Agbaegbu Iweka, Sharada M. Tilve, Caitlin P. Mencio…·Herbert M. Geller

The paper shows that PLPPR1 increases cell adhesion by modulating RhoA/Rac1 activity through its interaction with RhoGDI, overcoming inhibitory effects of CSPGs and LPA.

2 citations

𝕏 PostBluesky