Petra Majerová

This study identifies 15 novel tau-interacting proteins through yeast two-hybrid screening and validates their interactions, revealing potential biomarkers and therapeutic targets for neurodegenerative diseases.

The paper uses LC-MS/MS to analyze kynurenine pathway metabolites in plasma and brain tissue of heatstroke mice, revealing compartment-specific metabolic changes and potential biomarkers.

This study shows that alpha-synuclein overexpression causes different cellular responses and post-translational modifications in two neuronal cell models, highlighting context-dependent vulnerability in Parkinson's disease.

The paper shows that lipid metabolism changes with tauopathy progression, linking pathological tau to altered lipid production and microglial lipid droplet accumulation.

The paper develops a blood-cerebrospinal fluid barrier model from rat choroid plexus epithelial cells that exhibits functional tight junctions and expresses key transporters for drug discovery.

This study shows that chronic administration of KYNA-1, a kynurenic acid analog, reduces tau hyperphosphorylation and neuroinflammation in a tau transgenic rat model.