Evelien Smits

This study investigates the distinct roles of HIF-1 and HIF-2 in human NK cell activation under normoxic conditions, finding that HIF-1 inhibition reduces cytotoxicity and cytokine production while HIF-2 has no effect.

This study shows that DRP1 depletion protects NK cells from hypoxia-induced dysfunction by preserving mitochondrial function and cytotoxic activity.

The paper develops computational models to identify WT1-specific TCRs in AML patients and finds higher TCR diversity in remission compared to relapsed patients.