Author

Jöran Melis

University of AntwerpORCID 0000-0003-0776-7936Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

An WoutersiD· 2 shared Evelien SmitsiD· 2 shared Filip LardoniD· 2 shared Ho Wa Lau· 2 shared Jonas R.M. Van AudenaerdeiD· 2 shared Jorrit De WaeleiD· 2 shared Louize BrantsiD· 2 shared Tias VerhezeniD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersImmunology

An WoutersORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 27, 2025

HIF isoforms contribute distinctly during human NK cell activation

Jorrit De Waele, Tias Verhezen, Ho Wa Lau…·Evelien Smits

This study investigates the distinct roles of HIF-1 and HIF-2 in human NK cell activation under normoxic conditions, finding that HIF-1 inhibition reduces cytotoxicity and cytokine production while HIF-2 has no effect.

DOI 10.1101/2025.06.27.661904

humanexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 23, 2025

DRP1 depletion protects NK cells against hypoxia-induced dysfunction

Tias Verhezen, Astrid Van den Eynde, Peter Verstraelen…·Jorrit De Waele

This study shows that DRP1 depletion protects NK cells from hypoxia-induced dysfunction by preserving mitochondrial function and cytotoxic activity.

2 citations

humanproteomics

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