Gang Liu

This study identifies four molecular archetypes of lung adenocarcinoma premalignant lesions using bulk RNA and exome sequencing, linking proliferation-associated features to aggressive tumor outcomes.

This study validates a bronchial gene expression signature of bronchiectasis in nasal epithelium, showing similar gene expression changes in both tissues.

The paper identifies miRNAs and isomiRs associated with COPD and ILD through integrative network analysis of RNA-seq and SNP data from lung tissue samples.

This study uses single-cell RNA sequencing to analyze smoking effects on bronchial epithelial cell types, identifying molecular changes and a novel subpopulation linked to premalignant lesions.

This study evaluates a highly multiplexed RNA sequencing platform (SFL) and compares its performance to existing techniques, finding it outperforms 3DGE in coverage and differential gene expression detection.

The paper evaluates reference samples for genome-scale miRNA profiling and develops metrics and an online pipeline to assess measurement performance.