Author
Manchester Academic Health Science CentreORCID 0000-0001-9292-2472Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
Recent·Most cited
William H. Zammit, Lucy Le Maistre, Thomas A.E. Elliot…·Jonathan D. Worboys
The paper identifies TIGIT interactors and shows that inhibitory TIGIT signaling requires both CD155 ligation and TCR activation in T cells.
Lozan Sheriff, Alastair Copland, David A.J. Lecky…·David Bending
This study shows that PD-1 and Lag3 pathways additively regulate TCR signal duration and NFAT-dependent transcription during early CD4+ T cell activation, with co-blockade enhancing NFAT-dependent gene expression.