Author

Jean‐Philippe Semblat

Centre National de la Recherche ScientifiqueORCID 0000-0001-9321-5008Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:plant (other)· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Benoît GamainiD· 2 shared Christian DoerigiD· 2 shared Dominique DoriniD· 2 shared Romain HameliniD· 2 shared Anand SrivastavaiD· 1 shared Clara-Eva PaquereauiD· 1 shared Graziella MatesiciD· 1 shared Heledd Eavis· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Benoît GamainORCID

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2 papers

Recent·Most cited

BiochemistryPLoS PathogensPeer-reviewedJul 29, 2026

FIKK1, a member of the FIKK kinase family, phosphorylates VAR2CSA and regulates adhesion of Plasmodium falciparum-infected erythrocytes to the placental receptor CSA

Benoît Gamain, Jean‐Philippe Semblat, Heledd Eavis…·Dominique Dorin

This study identifies FIKK1 as a kinase that phosphorylates VAR2CSA, enhancing its binding to CSA and promoting placental malaria virulence.

DOI 10.1371/journal.ppat.1014108

plant (other)experimental assay

𝕏 PostBluesky

MicrobiologyPLoS PathogensPeer-reviewedJan 13, 2025

Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion

Dominique Dorin, Jean‐Philippe Semblat, Romain Hamelin…·Benoît Gamain

This study identifies Casein Kinase 2 as the kinase responsible for phosphorylating VAR2CSA, enhancing its CSA binding and infected erythrocyte adhesion.

7 citationstop 5%

humanplant (other)

𝕏 PostBluesky