Author

Maryann Zhao

Broad InstituteORCID 0000-0001-9325-4066Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aviv RegeviD· 2 shared Chris J. FrangiehiD· 2 shared Kathryn R. Geiger-SchulleriD· 2 shared Michael S. CuocoiD· 2 shared Orit Rozenblatt–RoseniD· 2 shared Pratiksha I. Thakore· 2 shared Adrienne LuomaiD· 1 shared Arindam Sett· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCell Biology

Aviv RegevORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 20, 2026

Perturb-ME: Scalable mechanism discovery from phenotype-enriched genome-wide screens

Hanchen Wang, Jiacheng Gu, Chris J. Frangieh…·Aviv Regev

Perturb-ME combines CRISPR screening and single-cell profiling to identify regulatory modules governing gene programs in melanoma.

1 citation

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GenomicsNature GeneticsPeer-reviewedMar 1, 2021

Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

Chris J. Frangieh, Johannes C. Melms, Pratiksha I. Thakore…·Benjamin Izar

The paper uses Perturb-CITE-Seq to identify novel immune evasion mechanisms in cancer by analyzing multi-modal single-cell data from patient-derived models.

276 citationstop 1%

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