Author

Adrienne Luoma

Dana-Farber Cancer InstituteORCID 0000-0001-9504-2403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Kai W. WucherpfennigiD· 2 shared Abdalla AhmediD· 1 shared Agne AntanaviciuteiD· 1 shared Albert BurgeriD· 1 shared Alexander V. PredeusiD· 1 shared Alexandre Denadai‐SouzaiD· 1 shared Alison SimmonsiD· 1 shared Andreas E. MooriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Kai W. WucherpfennigORCID

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3 papers

Recent·Most cited

The Human Gut Cell Atlas v1.0: A Unified, Community-Built Reference of Cellular Diversity Across the Gut

Kyle Kimler, Christopher Lance, Balázs Bohár, Abdalla Ahmed, Ran RZ Zhou, Raquel Bartolomé-Casado, Victòria Gudiño, Ricardo O. Ramirez Flores, Fredrik V. Junghus, Urs Mörbe, Diana Domańska, Michaela F. Mueller, Madelyn R. Moy, Ángela Sanzo-Machuca, Marton L. Olbei, , Kathryn E. Hamilton

The paper presents the Human Gut Cell Atlas v1.0, a unified reference of gut cell diversity, revealing how tissue structure influences cellular composition and enabling disease and organoid analysis.

bioRxiv · Oct 12, 2026 · PreprintSystems Biology

MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets

Xintao Qiu, Nadia Boufaied, Tarek Hallal, Avery S. Feit, Anna de Polo, Adrienne Luoma, Walaa Alahmadi, Janie Larocque, Giorgia Zadra, Yingtian Xie, Shengqing Stan Gu, Qin Tang, Yi Zhang, Sudeepa Syamala, Ji-Heui Seo, , David P. Labbé

This study shows MYC overexpression disrupts AR transcriptional pause release, promoting aggressive prostate cancer progression.

Nature Communications · May 13, 2022Peer-reviewedGenomics

Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

Chris J. Frangieh, Johannes C. Melms, Pratiksha I. Thakore, Kathryn R. Geiger-Schuller, Patricia Ho, Adrienne Luoma, Brian Cleary, Livnat Jerby‐Arnon, Shruti Malu, Michael S. Cuoco, Maryann Zhao, Casey R. Ager, Meri Rogava, Lila Hovey, Asaf Rotem, , Benjamin Izar

The paper uses Perturb-CITE-Seq to identify novel immune evasion mechanisms in cancer by analyzing multi-modal single-cell data from patient-derived models.

Nature Genetics · Mar 1, 2021Peer-reviewedGenomics