NeuroscienceJournal of Clinical InvestigationPeer-reviewed
GABAergic neurons and Nav1.1 channel hyperactivity: a novel neocortex-specific mechanism of cortical spreading depression.
Oana Chever, Sarah Zerimech, Paolo Scalmani…·Massimo Mantegazza
This study identifies a neocortex-specific mechanism of cortical spreading depression (CSD) initiated by hyperactivity of GABAergic neurons and NaV1.1 channel gain-of-function, linking it to Familial Hemiplegic Migraine type-3.
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