Author

Alexandre Loucif

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alex GutteridgeiD· 1 shared Andrew J. KnightsiD· 1 shared Ângela GonçalvesiD· 1 shared Anna L. Wilbrey· 1 shared Caroline Benn· 1 shared Daniel J. GaffneyiD· 1 shared Emma Impey· 1 shared Fabrice DupratiD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alex GutteridgeORCID

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Author profile →

2 papers

Recent·Most cited

GABAergic neurons and Nav1.1 channel hyperactivity: a novel neocortex-specific mechanism of cortical spreading depression.

Oana Chever, Sarah Zerimech, Paolo Scalmani, Louisiane Lemaire, Lara Pizzamiglio, Alexandre Loucif, Marion Ayrault, М. М. Крупа, Mathieu Desroches, Fabrice Duprat, Isabelle Léna, Sandrine Cestèle, Massimo Mantegazza

This study identifies a neocortex-specific mechanism of cortical spreading depression (CSD) initiated by hyperactivity of GABAergic neurons and NaV1.1 channel gain-of-function, linking it to Familial Hemiplegic Migraine type-3.

Journal of Clinical Investigation · Sep 7, 2021Peer-reviewedNeuroscience

Molecular and functional variation in iPSC-derived sensory neurons

Jeremy Schwartzentruber, Stefanie Foskolou, Helena Kilpinen, Julia Rodrigues, Kaur Alasoo, Andrew J. Knights, Minal J Patel, Ângela Gonçalves, Rita Ferreira, Caroline Benn, Anna L. Wilbrey, Magda Bictash, Emma Impey, Lishuang Cao, Sergio Laínez, , Daniel J. Gaffney

The paper maps regulatory variants in iPSC-derived sensory neurons, identifying genetic influences on gene expression, chromatin accessibility, and RNA splicing, with overlaps to disease associations.

Nature Genetics · Dec 10, 2017Peer-reviewedGenomics