Cell BiologyMolecular PsychiatryPeer-reviewed
Calorie Restriction Induces Degeneration of Neurons with Mitochondrial DNA Depletion by Altering ER-Mitochondria Calcium Transfer
Lingyan Zhou, Feixiang Bao, Jiajun Zheng…·Xingguo Liu
This study shows that calorie restriction exacerbates neuronal degeneration in mtDNA-depleted neurons by increasing ER-mitochondria calcium transfer, suggesting CR may not be beneficial for mitochondrial epilepsy.
8 citations