Gang Lü

This study shows that calorie restriction exacerbates neuronal degeneration in mtDNA-depleted neurons by increasing ER-mitochondria calcium transfer, suggesting CR may not be beneficial for mitochondrial epilepsy.

This study shows that Tmc7 deficiency in mice causes acrosome biogenesis defects and male infertility by disrupting Golgi function and ion homeostasis.

This study shows LSM14B is essential for MARDO assembly in mouse oocytes, leading to meiotic maturation failure and infertility.

This study shows that SSH2 is essential for acrosome biogenesis and male fertility in mice by regulating actin remodeling through COFILIN.

The paper uses single-cell RNA sequencing to analyze microglial transcriptomic diversity in subarachnoid hemorrhage, identifying distinct subgroups and their roles in neuroinflammation.

This study identifies CFAP53 as essential for sperm flagellum biogenesis, showing its role in male infertility and interactions with proteins in the manchette and sperm tail.

This study identifies ZCWPW1 as an H3K4me3 reader required for DSB repair and synapsis in mouse testes, showing its dependency on PRDM9 activity.